Ich denke mir das so: Quantität ersetzt eben keine Qualität.
Eine Studie vom Oktober aus Nature:
Anti-SARS-CoV-2 receptor-binding domain antibody evolution after mRNA vaccination
>>> https://www.nature.com/articles/s41586-021-04060-7
“SARS-CoV-2 infection produces B cell responses that continue to evolve for at least one year. During that time, memory B cells express increasingly broad and potent antibodies that are resistant to mutations found in variants of concern”
Following vaccination
“Between prime and boost, memory B cells produce antibodies that evolve increased neutralizing activity, but there is no further increase in potency or breadth thereafter.”
>>> Schade eigentlich...
“Instead, memory B cells that emerge 5 months after vaccination of naive individuals express antibodies that are similar to those that dominate the initial response.”
>>>= Antigenerbsünde? Och...
“While individual memory antibodies selected over time by natural infection have greater potency and breadth than antibodies elicited by vaccination, the overall neutralizing potency of plasma is greater following vaccination”
>>> für kurze Zeit hat man also einen guten Schutz
“These results suggest that boosting vaccinated individuals with currently available mRNA vaccines will increase plasma neutralizing activity but may not produce antibodies with equivalent breadth to… convalescent individuals”
>>> Willkommen zu mehr Boostern in immer kürzeren Abständen. Pfizer und Co. sind sicherliche gerne behilflich.