In der Fachzeitschrift „Tumori Journal“ wurde am 11.11.2020 folgender Artikel veröffentlicht: „Unexpected detection of SARS-CoV-2 antibodies in the prepandemic period in Italy“.
Abstract
There are no robust data on the real onset of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and spread in the prepandemic period worldwide. We investigated the presence of SARS-CoV-2 receptor-binding domain (RBD)–specific antibodies in blood samples of 959 asymptomatic individuals enrolled in a prospective lung cancer screening trial between September 2019 and March 2020 to track the date of onset, frequency, and temporal and geographic variations across the Italian regions. SARS-CoV-2 RBD-specific antibodies were detected in 111 of 959 (11.6%) individuals, starting from September 2019 (14%), with a cluster of positive cases (>30%) in the second week of February 2020 and the highest number (53.2%) in Lombardy. This study shows an unexpected very early circulation of SARS-CoV-2 among asymptomatic individuals in Italy several months before the first patient was identified, and clarifies the onset and spread of the coronavirus disease 2019 (COVID-19) pandemic. Finding SARS-CoV-2 antibodies in asymptomatic people before the COVID-19 outbreak in Italy may reshape the history of pandemic.
Link: https://doi.org/10.1177/0300891620974755
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Im Wesentlichen geht es darum, dass bei der nachträglichen Untersuchung der Blutproben eines prophylaktischen Lungenkrebsscreenings in Italien von Sept. 2019 - Feb. 2020 SARS-CoV-2 RBD Antikörper schon in den Septemberproben nachgewiesen wurden.